Search results for " cytocompatibility"

Hydroxyapatite/Chitosan/Collagen coatings through galvanic coupling

In this work, the attention was focused on Hydroxyapatite/ Chitosan/Collagen composite as biocoatings for application in orthopaedic devices. Hydroxyapatite was selected for its osteoconductivity due to its chemical structure similar to bones. Collagen has the same function since 90-95% of bone matrix is constituted of collagen fibers. Furthermore, chitosan are largely used yet in medical field (e.g. antibacterial agent or drug deliver) and in this work were used to create a synergic interaction with hydroxyapatite and collagen to increase the strength and bioactivity of coating. Coatings were fabricated by galvanic deposition process that has different advantages an it does not require ext…

The Cytocompatibility of Silver Diamine Fluoride on Mesenchymal Stromal Cells from Human Exfoliated Deciduous Teeth : An In Vitro Study

2022

Silver diamine fluoride (SDF) has been used for many years for the treatment of caries, and minimally invasive dentistry concepts have made it popular again. The fact that its application does not require the administration of anesthesia makes its use in children more desirable. The aim of this study was to determine the cytotoxicity of two new commercial SDF products: Riva Star (SDI Dental Limited) and e-SDF (Kids-e-Dental) on mesenchymal stromal cells from human exfoliated deciduous teeth (SHEDs). SHEDs were exposed to SDF products at different concentrations (0.1%, 0.01% and 0.005%). Then different assays were performed to evaluate their cytocompatibility on SHEDs: IC50, MTT, cell migrat…